contusion, subchondral or chondral injury with and without meniscal tear and with and without ligamentous

Osteoarthritis (OA) is the most important rheumatic disease aff ecting mankind. Where risk factors have been identifi ed, such as in knee and hip OA, with few exceptions, no prevention strategies are well substan tiated enough or have proven benefi t to justify wide spread dissemination. Th e major risk factors for knee OA are advanced age, injury and obesity [1]. However, there is limited or no evidence that they are modifi able or to what degree modifying them is eff ective or what this would cost in primary prevention (avoiding development of knee OA) or secondary prevention (detecting knee OA early to treat to prevent symptoms and progressive disease). Th e notable exception is the growing epidemic of (sports) injury related knee OA. Th e purpose of this review is to detail the biological and clinical data that make this subset of OA an attractive public health target.